Table 3.

Percentage increase in serum copeptin levels per SD increase in HOMA-IR scores among patients with CKD and controls

ModelPercentage Change (95% CI)
Patients with CKDControls
Model 12 (−11 to 15)27 (4 to 51)
Model 25 (−10 to 20)17 (−5 to 39)
  • Model 1 is adjusted for age, sex, and serum osmolality. Model 2 is adjusted for model 1 variables, BMI, log IL6, and log leptin/adiponectin ratio. P interaction (HOMA-IR×CKD)=0.32. HOMA-IR, homeostasis assessment model of insulin resistance.