Table 5.

Correlogram of baseline biomarker levels and histologic measurements in patients with lupus nephritis

% Interstitial Fibrosis% Tubular AtrophyInterstitial Mononuclear Cell Infiltration
uPRO-C3/Crea0.1920.1890.059
uPRO-C6/Crea0.3840.3630.356
uC3M/Crea−0.430a−0.503a−0.257
PRO-C30.3720.2800.302
PRO-C60.412a0.3770.477a
  • u, urine; PRO-C3, biomarker of interstitial collagen type III; PRO-C6, biomarker of interstitial collagen type VI; C3M, biomarker of collagen type III.

  • a Moderate correlation (rho: 0.4–0.7).