Table 2.

Highest urine albumin and urine protein, and lowest plasma albumin levels from 1 month before to 1 month after first-time hospital-recorded nephrotic syndrome, and first-time recorded nephrotic proteinuria and hypoalbuminemia during 2004–2018

CharacteristicPatients with Hospital-Recorded NSPatients with Nephrotic Proteinuria and Hypoalbuminemia
Overall, n (%)1139 (100)5268 (100)
Any proteinuria/albuminuria test ±31 d from index date, n (%)842 (74)5268 (100)
Any UACR test ±31 d from index date, n (%)a603 (53)3809 (72)
 Days from highest recorded UACR, median (IQR)b0 (−5 to 12)0 (0–0)
Highest recorded UACR (mg/mmol), median (IQR)b468 (224–736)348 (262–527)
Any UPCR test ±31 d from index date, n (%)a30 (3)218 (4)
 Days from highest recorded UPCR, median (IQR)b1 (−2 to 23)0 (0–3)
Highest recorded UPCR (mg/mmol), median (IQR)b328 (1–634)224 (0–472)
Any AER test ±31 d from index date, n (%)a311 (27)1391 (26)
 Days from highest recorded AER, median (IQR)b1 (0–5)0 (−1 to 2)
 Highest recorded AER (g/d), median (IQR)b5.3 (3.0–8.4)3.9 (2.7–6.0)
Any PER test ±31 d from index date, n (%)a297 (26)1453 (28)
 Days from highest recorded PER, median (IQR)b2 (−3 to 7)0 (0–1)
 Highest recorded PER (g/day), median (IQR)b6.8 (4.1–10.3)5.4 (4.0–8.4)
Any p-albumin test ±31 d from index date, n (%)a1087 (95)5268 (100)
 Days from lowest recorded p-albumin, median (IQR)b2 (−1 to 9)0 (0–4)
 Lowest recorded p-albumin (g/L), median (IQR)b23 (17–30)29 (24–32)
  • Any percentage in the table is a column percentage. NS, nephrotic syndrome; IQR, inter quartile range; UACR, urine albumin-creatinine ratio; UPCR, urine protein-creatinine ratio; AER, urine albumin excretion rate; PER, urine protein excretion rate; p-albumin, plasma albumin.

  • a Each patient may have more than one type of proteinuria test (UACR, UPCR, AER, PER), and the highest measured level of each test was tabulated, so column numbers do not add up to 100%.

  • b Among patients with available tests ±31 days from the index date.