Table 2.

Percentage increase in serum copeptin levels per SD decrease in insulin sensitivity index among patients with CKD and controls

ModelPercentage Change (95% CI)
Patients with CKDControls
Model 134 (0.5 to 68)0.05 (−7 to 17)
Model 239 (3 to 75)1 (−12 to 15)
  • Model 1 is adjusted for age, sex, and serum osmolality. Model 2 is adjusted for model 1 variables, BMI, log IL6, and log leptin/adiponectin ratio. P interaction (ISI×CKD)=0.03.