Table 3.

Donor and recipient characteristics associated with de-novo post-transplant diabetes mellitus in univariate analysis

Risk FactorsValue levelUnivariateMultivariablea
Hazard Ratio (95% Confidence Interval)bP valueHazard Ratio (95% Confidence Interval)
Donor risk factors
 Age5 year increase1.04 (0.99 to 1.09)0.13
 Weight (kg)5 kg increase1.02 (0.98 to 1.05)0.46
 BMI (kg/m2)5 unit increase1.01 (0.92 to 1.11)0.84
 ObesityYes vs no0.91 (0.66 to 1.24)0.55
 Donor KDPI10 unit increase1.02 (0.97 to 1.08)0.43
 Hepatitis CYes vs no1.13 (0.46 to 2.75)0.79
Recipient risk factors (at time of transplant)
 Age5 year increase1.12 (1.06 to 1.18)<0.001a1.14 (1.07 to 1.20)
 Weight (kg)5 kg increase1.03 (1.00 to 1.06)0.03
 BMI (kg/m2)5 unit increase1.18 (1.05 to 1.33)0.006a1.19 (1.05 to 1.34)
 Black raceYes vs No1.05 (0.78 to 1.39)0.761.15 (0.85 to 1.56)
 HLA mismatches1 unit increase1.01 (0.91 to 1.13)0.790.97 (0.87 to 1.09)
  • BMI, body mass index.

  • a From a multivariable model with recipient age, BMI, Black race, and HLA mismatch.

  • b Cox regression model; obesity defined as BMI >30 kg/m2.