Table 2.

Results in sham mice at a glance

ParametersSox6-WT MiceSox6-KO Mice
BPNormalNormal
Prorenin and renin expressionDid not increase in both sham and in contralateral kidneys, especially with IHC and ISHHard to detect in both sham and in contralateral kidneys, especially with IHC and ISH
JG cell recruitmentNo JG cell recruitment in both sham and in contralateral kidneysNo JG cell recruitment in both sham and in contralateral kidneys
NGAL expressionDecreased expression in both sham and in contralateral kidneysDecreased expression in both sham and in contralateral kidneys
Creatinine clearancePreservedPreserved
  • WT, wild type; KO, knockout; IHC, immunohistochemistry; ISH, in situ hybridization; JG, juxtaglomerular; NGAL, neutrophil gelatinase-associated lipocalin.