Table 3.

Sensitivity analysis and likelihood ratio for both KDIGO-defined AKI on day 0–1 and categories of KeGFR for prediction of day-3 severe AKI

Day 0–1SensitivitySpecificityPPVNPVLR
No AKI/KDIGO 141 (29–53)13 (11–16)5 (4–6)67 (60–72)0.5 (0.4–0.6)
KDIGO 2 or 359 (47–71)87 (84–89)33 (27–40)95 (94–96)4.5 (3.4–5.9)
KeGFR >120 ml/min per 1.73 m2 5 (1–13)52 (48–56)1 (0–3)83 (82–85)0.1 (0.04–0.3)
KeGFR <120 ml/min per 1.73 m2 85 (75–92)47 (43–51)15 (14–17)97 (94–98)1.6 (1.4–1.8)
KeGFR <90 ml/min per 1.73 m2 70 (59–80)80 (77–83)28 (24–33)96 (94–97)3.6 (2.9–4.4)
KeGFR <60 ml/min per 1.73 m2 57 (45–69)96 (95–98)64 (53–74)95 (94–96)16.1 (10.3–25.2)
  • KDIGO, Kidney Disease Improving Global Outcomes; KeGFR, kinetic eGFR; PPV, positive predictive value; NPV, negative predictive value; LR, likelihood ratio.