Table 3.

Univariate Cox analysis on the effect of various etiologies on the clinical outcome of patients with cryoglobulinemia

EtiologyPrimary Composite End PointProgression to ESKDOverall Mortality
Unadjusted Hazard Ratio (95% Confidence Interval)P ValueUnadjusted Hazard Ratio (95% Confidence Interval)P ValueUnadjusted Hazard Ratio (95% Confidence Interval)P Value
Hepatitis B0.59 (0.41 to 0.85)0.0040.46 (0.25 to 0.83)0.010.54 (0.34 to 0.87)0.01
Hepatitis C0.79 (0.55 to 1.16)0.230.57 (0.31 to 1.05)0.070.67 (0.42 to 1.08)0.10
Paraproteinemia1.23 (0.53 to 12.81)0.632.29 (0.69 to 7.61)0.183.36 (1.51 to 7.46)0.003