Table 1.

Handout for patients when initiating sodium-glucose cotransporter-2 inhibitor therapy

It is recommended that the patients follow the recommendations stated below and must contact their provider if they have any questions or concerns
Increase in urine output
 You may notice an increase in your urine output after starting this medication
 Monitor your weight at home
BP
 Monitor your BP at home because this medicine may lower BP
 Inform your doctor if your BP is too low, or if you experience light headedness or dizziness
Blood glucose
 Monitor your blood glucose level at home because this medicine may lower blood glucose
 Inform your doctor if your blood glucose is low
Follow the “sick-day rule”
 Do not take this medicine on days that you are unable to eat because you are feeling sick due to fever, infection, poor appetite, nausea, vomiting, or diarrhea
 You can resume the medicine once you are able to eat and drink
 If you continue to feel sick, then call your doctor because you may need to have blood tests to rule out diabetic ketoacidosis
Stop the medication 3–4 d before a scheduled surgery that requires you to be “nothing by mouth” (meaning you are instructed to not eat or drink anything for several h before your surgery)
Avoid very low carbohydrate and keto diets because they may increase the risk of diabetic ketoacidosis
Wound on your feet or legs
 If you notice a wound, ulcer, or skin breakdown on your feet or legs, then hold this medicine and inform your doctor
Burning or pain during urination
 If you experience pain or burning on urination, then inform your doctor because you may need further evaluation
Redness or itching in the genital area, or foul-smelling vaginal or penile discharge
 Keep the genital area clean
 If you notice redness or itching in the genital area, or foul-smelling vaginal or penile discharge, then inform your doctor; you may need a cream or oral medication to treat an underlying infection