Table 4.

Cox regression analysis displaying individual hazard ratio for each performance-based functional assessment and the summary score associated with each outcome and the incremental reduction in variance for each assessment in the model.

ModelDeathESKDESKD or 50% Decline in GFRDeath, ESKD, or 50% Decline in GFR
P ValueHR (95% CI)−2 Log LikelihoodChi-Squared Score P ValueHR (95% CI)−2 Log LikelihoodChi-Squared Score P ValueHR (95% CI)−2 Log LikelihoodChi-Squared Score P ValueHR (95% CI)−2 Log LikelihoodChi-Squared Score
Unadjusted model591.40420.63561.161127.03
Adjusted model569.5321.87352.7467.89487.1074.071063.1463.89
SPPB0.0032.43 (1.36 to 4.34)560.129.410.420.82 (0.40 to 1.68)352.090.650.341.36 (0.72 to 2.55)486.190.910.0021.96 (1.28 to 2.99)1053.269.88
M3SE0.211.49 (0.80 to 2.77)567.931.610.621.20 (0.59 to 2.44)352.490.250.921.03 (0.55 to 1.93)487.090.010.301.26 (0.81 to 1.95)1062.051.09
IADL0.061.71 (0.97 to 2.99)566.183.350.170.58 (0.27 to 1.25)350.652.080.050.49 (0.24 to 1.00)482.774.330.930.98 (0.64 to 1.50)1063.130.01
Summary score0.012.07 (1.16 to 3.69)563.346.200.560.81 (0.39 to 1.66)352.400.340.620.85 (0.46 to 1.59)486.850.260.131.39 (0.91 to 2.10)1060.812.33
  • Adjusted model includes baseline values for age, sex, race, body mass index, mean arterial pressure, baseline GFR, diabetes, cardiovascular disease, cancer, education, and income. HR, hazard ratio; SPPB, Short Physical Performance Battery; M3SE, Modified Mini-Mental Status Exam; IADL, Lawton Instrumental Activities of Daily Living.