Table 4.

C-statistics in groups with albumin-creatinine ratio, protein-to-creatinine ratio/dipstick, and no urine testing within 3 yr

Health Care Organization IdentificationGroup 1: Has Albumin-Creatinine Ratio TestGroup 2: Has Protein-To-Creatinine Ratio TestGroup 3: Has Proteinuria Dipstick TestGroup 4: Has No Albuminuria Test
Three-variableFour-variableThree-variableFour-variableThree-variableFour-variableThree-variable
10.8400.8880.8940.9220.872
20.8600.9120.9020.9170.915
30.7940.8360.9150.9350.865
40.8860.9090.9110.9290.931
50.8690.907
60.8560.8940.7900.8040.8760.8880.885
70.8660.9200.900
80.9050.9210.9200.9400.911
90.8520.8980.931
100.8260.8610.8400.8640.8760.8950.887
110.8620.9190.8400.8630.877
120.8590.8920.9250.9370.869
130.8150.8790.8670.8880.8670.892
140.8430.8840.8450.8770.8510.8410.903
150.8940.9120.8870.9000.923
160.8670.9000.8030.8300.9160.9160.889
170.8640.9030.8850.9020.901
180.8710.9250.8400.8660.926
190.8800.8970.8170.8230.8550.8640.897
200.8670.9090.8980.9140.921
210.8540.8910.8790.8870.922
220.8120.8490.8980.9060.881
230.8670.8970.9020.9170.960
240.9030.9300.9010.9180.868
250.8910.9320.8920.9130.927
260.8330.8770.8170.8240.882
270.8510.9050.8970.9080.862
280.8380.8890.7630.7890.8510.8680.867
290.8520.8760.8840.8940.889
300.7620.8540.8790.8890.898
310.8440.8850.9040.9150.906
320.8420.8820.8770.8680.921
330.8600.8950.8350.8330.930
340.8700.9150.8430.8500.932
350.8290.8810.8520.8840.8590.8810.889
360.8440.8830.8610.8780.881
370.8330.8680.7940.8140.8870.9010.929
380.8970.930
390.8450.8930.8690.8880.887
Median C-statistic0.8560.8950.8280.8470.8850.8970.899
Meta-analyzed difference in C-statisticMeta-analyzed difference in C-statisticMeta-analyzed difference in C-statistic
0.039 (0.036–0.043)0.022 (0.017–0.026)0.012 (0.010–0.015)
  • Group 1, available ACR test. Group 2, available PCR, but no available ACR. Group 3, available urine dipstick protein level measurement, but no available ACR or PCR. Group 4, no form of albuminuria measured. Bold indicates that the difference in C-statistic between the 4-variable and 3-variable KFRE in the group is statistically significant. ACR, albumin-creatinine ratio; PCR, protein-to-creatinine ratio.