Table 1.

Demographic and clinical characteristics of study participants

CharacteristicsTotalSteroid SensitivitySteroid ResistanceP Valuea
Sex, n (%)80 (100)67.00 (84)13.00 (16)
 Male52 (100)47 (90)5 (10)0.03
 Female28 (100)20 (71)8 (29)
Age (yr), mean (SD)4.72 (3.84)4.88 (3.98)3.87 (3.27)0.39
Renal pathology, n (%)
 Minimal change57 (100)49 (86)8 (14)
 FSGS3 (100)0 (0)3 (100)
 Mesangial proliferative glomerular nephritis2 (100)0 (0)2 (100)
 Unknown18 (100)18 (100)0 (0)
Selectivity index (n=73), mean (SD)0.08 (0.11)0.07 (0.11)0.10 (0.10)0.42
Serum total protein (g/dl, n=79), mean (SD)4.22 (0.55)4.2 (0.53)4.31 (0.66)0.47
Serum albumin (g/dl, n=80), mean (SD)1.38 (0.54)1.33 (0.52)1.59 (0.61)0.12
TP/Alb ratio (n=79), mean (SD)3.64 (1.95)3.76 (2.07)3.04 (1.02)0.22
eGFR (ml/m2 per hour, n=72), mean (SD)127.77 (56.41)131.43 (57.5)109.49 (48.64)0.22
Total cholesterol (mg/dl, n=76), mean (SD)402.28 (104.48)396.34 (105.41)437.36 (95.74)0.23
Serum IgG (mg/dl, n=80), mean (SD)330.39 (254.22)322.44 (195.05)371.35 (462.65)0.53
Serum IgM (mg/dl, n=80), mean (SD)167.00 (72.74)171.33 (75.25)144.65 (55.18)0.23
Serum IgA (mg/dl, n=77), mean (SD)121.39 (62.99)124.06 (65.63)108.29 (47.86)0.41
Complement C3 (mg/dl, n=75), mean (SD)133.72 (31.66)132.77 (33.32)138.25 (22.56)0.57
Urinary total protein (mg/dl, n=79), mean (SD)31.27 (10.03)31.98 (10.62)27.89 (5.6)0.18
Urinary TP/Cre ratio (n=78), mean (SD)15.66 (11.62)15.56 (11.99)16.16 (9.98)0.87
Microscopic hematuria (n=69), n (%)
 Negative38 (100)32 (56)6 (50)0.92
 Positive31 (100)25 (45)6 (50)
  • N=80. TP, total protein; Alb, albumin; Cre, creatinine.

  • a Chi-squared test.