Table 4.

Change in kidney biomarkers and major adverse kidney events

Δ BiomarkerMajor Adverse Kidney Events at Hospital Discharge (n=49)No Major Adverse Kidney Events at Hospital Discharge (n=57)P Value
Δ serum NGAL (ng/ml)12 (−143 to 58) (n=23)−84 (−363 to −41) (n=13)0.01
Δ urinary NGAL (ng/mg Cr)−41 (−2491 to 144) (n=19)−20 (−869 to 80) (n=13)0.92
Δ serum cystatin C (ng/ml)−82 (−1121 to 734) (n=23)−87 (−232 to 142) (n=13)0.68
Δ urinary cystatin C (ng/mg Cr)−112 (−545 to 552) (n=19)18 (−547 to 105) (n=13)0.89
Δ urinary KIM-1 (ng/mg Cr)0 (−6 to 2) (n=19)−1 (−8.5 to 0) (n=13)0.19
  • Δ, value at 5–7 d (Time 2) minus value at 24–48 h (Time 1). NGAL, neutrophil gelatinase-associated lipocalin; Cr, creatinine; KIM-1, kidney injury molecule-1. Results are shown as median (interquartile range).