Table 3.

Cox proportional hazard model for mortality, cardiovascular, stroke, and coronary events in American Indians from the Strong Heart Study (1989–1999) with addition of clinical features as confounders/mediators

EventExposure: CKDExposure: Loss >20 ml/min
Yr FU, Mean (SD)New EventsIncidence RateHazard Ratio95% Confidence IntervalP valueHazard Ratio95% Confidence IntervalP value
Mortality13.7 (6.4)11980.04181.410.95 to to 3.000.05
All CVD17.7 (4.5)6830.01961.020.64 to 1.640.931.720.90 to 3.320.10
Stroke19.0 (2.3)1740.00441.930.92 to to 5.160.40
CHF18.7 (2.9)2560.00671.310.57 to 3.010.522.700.90 to 8.010.08
  • Models excluding prevalent CVD, stroke, and/or CHF as relevant; adjusted for baseline eGFR and/or eGFR slope as relevant; all adjusted for age, sex, field center, smoking, alcohol use, BMI, education, income, hypertension, and diabetes. FU, follow up; CVD, cardiovascular disease; BMI, body mass index.