Table 3.

Side-by-side performance characteristics between AlloSure and Prospera for cellular rejection at 0.5% and 1.0% threshold

Diagnostic Category0.5% Threshold1.0% Threshold
AlloSureProsperaAlloSureProspera
Sensitivity (95% exact CI)0.76 (0.40 to 0.97)0.56 (0.21 to 0.86)0.44 (0.14 to 0.79)0.44 (0.14 to 0.79)
Specificity (95% exact CI)0.53 (0.27 to 0.79)0.53 (0.27 to 0.79)0.80 (0.52 to 0.96)0.60 (0.32 to 0.84)
PPV (95% exact CI)0.50 (0.23 to 0.77)0.42 (0.15 to 0.72)0.57 (0.18 to 0.90)0.40 (0.12 to 0.74)
NPV (95% exact CI)0.80 (0.44 to 0.97)0.67 (0.35 to 0.90)0.71 (0.44 to 0.90)0.64 (0.35 to 0.87)
  • PPV, positive predictive value; NPV, negative predictive value.