Table 1.

Summary of studied subjects

ConditionNumber of SubjectseGFR Range (ml/min per 1.73 m2)Plasma Neu5Ac (ng/ml)
FSGS118–82310–1260
Minimal change disease192204
Mesangial proliferative Glomerulonephritis160353
p-ANCA vasculitis146317
Membranous nephropathy128819
IgA nephropathy120546
GNE myopathy (11)1985–155109–206
Normal control (13)6>90100–200
  • Subjects included those with kidney disease who participated in this study (n=16), those with GNE myopathy (n=19), and controls (n=6) with normal kidney function who participated in our previously published studies. The same Neu5Ac bioanalytical liquid chromatography and tandem mass spectrometry assay was used. Neu5Ac, N-acetylneuraminic acid/sialic acid; p-ANCA, perinuclear ANCA.