Table 2.

Clinical studies and databases with renal histopathology and residential context information

Clinical Studies and DatabasesYearsLocationsSample SizeDemographic CharacteristicsBiopsy Scored?
Age, yr, Mean ± Standard DeviationWhite, %Women, %
Aging Kidney Anatomy Study: Healthy Living Kidney Donors (6365)2011–2021Multiple USAdults: 2453aAdults: 44±129459Complete
Aging Kidney Anatomy Study: Tumor Nephrectomy Patients (65)2011–2021Multiple USAdults: 780aAdults: 64±12NR36Complete
Boston Kidney Biopsy Cohort (66)2006–2016Boston, MAAdults: 676Adults: 52±176453Complete
Clinical Phenotyping and Resource Biobank Core (Patients with Renal Disease) (67)2009–2018Multiple USAdults: 1374; peds: 271Adults: 55±20; peds: 11±45252In progress
Cure Glomerulonephropathy Consortium (68)2014–2020Multiple USAdults: 1680a; peds: 720Adults: 46±17; peds: 10±46743In progress
Nephrotic Syndrome Study Network (69,70)2010–2019Multiple US, CanadaAdults: 355; peds: 313Adults: 46±16; peds: 6±55441In progress
  • Each scored database contains pathology kidney data including glomerular size, percentage glomerulosclerosis, percentage of interstitial fibrosis and tubular atrophy, measures for vascular disease, and clinical indicators of renal function (e.g., creatinine, creatine-based eGFR, and urinary protein/albumin). Some databases have more extensive kidney pathology data as well as additional clinical data, genomic data, and molecular data. US, United States; peds, pediatric patients.

  • a Recruitment is ongoing; sample size reflects current enrollment.