Table 3.

Comparisons in clinical characteristics, initial vital signs, and inflammatory markers in those alive compared with those who died

CharacteristicAliveDeceasedP Value
Patients, n8232
Age, yr, median (IQR)66 (56 to 74)61 (48 to 67)0.05
Sex, n (%)
 Female31 (38)13 (41)0.8
 Male51 (62)19 (59)
Race/ethnicity, n (%)
 Black43 (52)19 (59)0.4
 Hispanic32 (82)9 (28)0.3
 White3 (57)3 (9)1.0
 Other4 (50)1 (3)0.8
Dialysis vintage (yr), median (IQR)3.2 (1 to 6.1)3.2 (2.1 to 4.8)0.5
Vascular access, n (%)
 AVF57 (70)26 (81)0.2
 AVG9 (11)3 (9)0.8
 Central vein catheter (tunneled)16 (20)3 (9)0.2
Clinical comorbidities
 Hypertension, n (%)73 (89)29 (91)0.9
 Diabetes mellitus, n (%)53 (65)23 (72)0.5
 Cardiovascular disease, n (%)41 (57)16 (50)0.8
 Stroke, n (%)16 (20)9 (28)0.3
 Pulmonary disease, n (%)30 (37)10 (31)0.6
 Hepatitis C, n (%)14 (17)5 (16)0.9
 Total number of comorbidities, median (IQR)3 (3–5)3.5 (3–5)0.4
Initial vital signs, median (IQR)
 Temperature (°F)99.4 (98.4 to 100.8)100.3 (98.6 to 101.1)0.6
 Respiratory rate (breaths/min)19 (18 to 22)20 (18.3 to 23.5)0.03
 Heart rate (beats/min)88 (74 to 103)93 (76.5 to 105.5)0.7
 Pulse oximetry (%)96 (95 to 98)96 (90 to 99)0.04
Initial laboratory data, median (IQR)
 White cell count (k/µl), n=1145.5 (3.9 to 7.6)6.7 (4.7 to 9.5)0.6
 Lymphocyte (%), n=11416 (9.5 to 22)9.5 (6.8 to 14.3)0.002
 Procalcitonin (ng/ml), n=602.3 (1 to 6.8)7 (1.5 to 11.7)0.06
 C-reactive protein (mg/dl), n=1029.3 (3.8 to 18.9)14.2 (10.2 to 27)0.005
 D-dimer (µ/ml), n=390.3 (1.9 to 4.6)1.4 (0.9 to 6.1)0.5
 LDH (U/L), n=106329 (258 to 449)487.5 (346 to 613)0.05
 Ferritin (ng/ml), n=832880 (1698 to 4512)3812 (2839 to 8311)0.005
 IL-6 (pg/ml), n=4648.2 (22.8 to 148.9)132 (66.3 to 234.4)0.04
  • Numbers reported in table are n (%). Laboratory data are reported as median (IQR) or n (%). IQR, interquartile range; AVF, arteriovenous fistula; AVG, arteriovenous graft; LDH, lactate dehydrogenase.