Table 1.

Normalized counts of all genes studied via targeted RNA sequencing in 3-month-old male rats

GeneVehicle MaleSildenafil MaleP Value
Agtr1a0.0150.0120.46
Cat1.0411.4790.06
Col3a10.1040.080.48
Edn10.0070.0090.31
Ednra0.0010.0010.73
Ednrb0.0590.0530.51
Gpx20.0090.0200.07
Gss0.5950.8640.28
Hmox10.0070.0060.58
Hmox2UndUnd
Hif3a0.0000.0010.02a
Il10UndUnd
Il17aUndUnd
Il6UndUnd
Havcr10.0230.0330.32
Nox40.1510.1530.96
Nphs10.0270.0270.97
Lcn20.0090.010.77
Nos2UndUnd
Nos30.0050.0040.28
Pde5a0.0050.0080.17
Nphs20.1030.1190.53
Prkg2UndUnd
Atp6ap20.1130.157<0.001a
S100a40.0310.0260.61
Sod12.6092.8750.53
Sod20.6270.6660.33
Sod30.3530.5080.05a
Tgfb10.0190.019>0.99
Timp10.0330.033>0.99
TnfUndUnd
Vim0.1410.1490.82
  • Und, undetectable; —, not applicable.

  • a P<0.05 versus vehicle.