Table 1.

oATP attenuated T cell–mediated rejection and antibody-mediated rejection

Animal IdentifierTreatmentitvgptcC4dCortical Necrosis/Interstitial HemorrhageDiagnosis
1oATP222233IIb TCMR and ABMR
2oATP321333IIa TCMR and ABMR
3oATP323333III TCMR and ABMR
4oATP321323IIa TCMR and ABMR
5oATP321333IIa TCMR and ABMR
6oATP321333IIa TCMR and ABMR
7oATP322333IIb TCMR and ABMR
8oATP311333IIa TCMR and ABMR
9Control332323+IIb TCMR and ABMR
10ControlNANANANANA3+ABMR
11ControlNANANANANA3+ABMR
12ControlNANA3NANA3+ABMR
13ControlNANANANANA3+ABMR
14Control333333+III TCMR and ABMR
15CsA100213ABMR
16CsA102213ABMR
17CsA100213ABMR
18CsA000233ABMR
19CsA100113ABMR
20CsA210213Ia TCMR and ABMR
  • oATP, oxidized ATP; TCMR, T cell–mediated rejection; ABMR, antibody-mediated rejection; NA, not assessed due to diffuse kidney necrosis; CsA, cyclosporine A. Ia, IIa, IIb, III are grades of rejection, with Ia being the least amount of rejection and III being the most in this table. Ia<IIa<IIb<III.