PT - JOURNAL ARTICLE AU - Jo, Sang Kyung TI - Kidney-Gut crosstalk in acute kidney injury AID - 10.34067/KID.0007722020 DP - 2021 Jan 01 TA - Kidney360 PG - 10.34067/KID.0007722020 4099 - http://kidney360.asnjournals.org/content/early/2021/02/22/KID.0007722020.short 4100 - http://kidney360.asnjournals.org/content/early/2021/02/22/KID.0007722020.full AB - Bidirectional relationship exist between kidney and intestine during AKI. Kidney IRI provoked dysbiosis, immune cell activation and leaky gut while dysbiosis (as a whole) act as an important modifier of AKI severity. Targeting the intestine/microbiota might provide a new avenue for the prevention and treatment of AKI.