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Brief Communication

Apixaban vs no anticoagulation by P2Y12 inhibitor prescription status in dialysis patients with atrial fibrillation

Thomas A. Mavrakanas and David M. Charytan
Kidney360 August 2022, 10.34067/KID.0003002022; DOI: https://doi.org/10.34067/KID.0003002022
Thomas A. Mavrakanas
1McGill University, Canada
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  • For correspondence: thomas.mavrakanas@mcgill.ca
David M. Charytan
2Nephrology, New York University Medical Center, United States
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Key Points

  • In patients with AF on dialysis, the incidence of stroke was similar with apixaban or no anticoagulation, regardless of P2Y12 prescription.

  • In patients with AF on dialysis who were on a P2Y12 inhibitor, apixaban increased the risk of bleeding, compared with no anticoagulation.

  • The incidence of MI or ischemic stroke was similar with apixaban or no anticoagulation, regardless of P2Y12 prescription status.

Abstract

This is an Early Access article. Please select the PDF button, above, to view it.

  • apixaban
  • P2Y12 inhibitor
  • atrial fibrillation
  • dialysis
  • stroke
  • bleeding
  • Prescriptions
  • Received April 25, 2022.
  • Revision received July 25, 2022.
  • Accepted July 25, 2022.
  • Copyright © 2022 American Society of Nephrology
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Kidney360: 3 (7)
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Vol. 3, Issue 7
28 Jul 2022
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Apixaban with P2Y12 inhibitors in dialysis
Thomas A. Mavrakanas, David M. Charytan
Kidney360 Aug 2022, 10.34067/KID.0003002022; DOI: 10.34067/KID.0003002022

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Apixaban with P2Y12 inhibitors in dialysis
Thomas A. Mavrakanas, David M. Charytan
Kidney360 Aug 2022, 10.34067/KID.0003002022; DOI: 10.34067/KID.0003002022
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More in this TOC Section

  • Exacerbation of Racial Disparities in Living Donor Kidney Transplantation During the COVID-19 Pandemic
  • Impact of Medication Reconciliation by a Dialysis Pharmacist
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Keywords

  • apixaban
  • P2Y12 inhibitor
  • atrial fibrillation
  • dialysis
  • stroke
  • bleeding
  • Prescriptions

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